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102 cmfor men or > 88 cm for women) and waist/hip ratio (WC divided by that of the hips of> 0.9 for men and > 0.85 for women)] and [30 generalized obese (GO) subjects (22males and 8 females; their mean± SD of age was 42.5± 8 years), their body massindex (BMI) was ≥ 30-34.9 kg/m2, with normal WC]. Serum levels of RBP-4 weremeasured by ELISA, serum levels of TT were measured by colorimetric methods,blood HbA1c%, lipid profiles and CRP were also determined. Subjects with AO hadsignificantly higher circulating RBP-4 and CRP levels compared to GO (p< 0.05 foreach). Total thiols levels were significantly lower in AO subjects compared to GO(p< 0.05). Total serum cholesterol, triglycerides and HbA 1c% increased with BMI,WC and waist/hip ratio (WHR), but the relations were statistically insignificant.Conclusion: The study revealed that RBP-4 is autonomously related to visceral fataccumulations and cardiovascular diseases. The study also revealed the beneficialeffect of TT against obesity and cardiovascular disease and the potential clinicalapplicability of RBP4 and total thiols in cardiovascular diseases.]]>
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