The present study included 45 subjects classified into three groups: Group I (control group) which comprised 15 healthy individuals, group II which comprised 15 patients with positive ELISA test for hepatitis C,but negative PCR test for HCV RNA and Group III which included 15 patients with positive ELISA test for hepatitis C and positive PCR test for HCV RNA. As regards IL-10 level the present study showed that there was highly significant increase in the level of IL – 10 in group II and III when compared with control group (p< 0.001) as positive ELISA test for hepatitis C and positive PCR test for HCV RNA was an indication to the activity of HCV. It just indicated that the patient was carrier of HCV infection.The study revealed a positive significant correlation between IL10 and ALT, AST, GGT and ALP. In conclusion, from the present study, it could be concluded that IL -10 as a marker of T- helper 2 activity increases with chronic hepatitis C and that increase is related to the increased chronicity of the disease so it may be a useful marker in diagnosis of hepatitis C patients.
H, Y., F, M., G, A., Ali, M., & A., H. (2008). Role of Serum Interleukin–10 as a Marker of T-helper 2 Activity in Egyptian Chronic Hepatitis C Patients. Bulletin of Egyptian Society for Physiological Sciences, 28(1), 141-152. doi: 10.21608/besps.2008.36844
MLA
Yousri H; Mohamed F; Amal G; Mohamed Ali; Haidy A.. "Role of Serum Interleukin–10 as a Marker of T-helper 2 Activity in Egyptian Chronic Hepatitis C Patients". Bulletin of Egyptian Society for Physiological Sciences, 28, 1, 2008, 141-152. doi: 10.21608/besps.2008.36844
HARVARD
H, Y., F, M., G, A., Ali, M., A., H. (2008). 'Role of Serum Interleukin–10 as a Marker of T-helper 2 Activity in Egyptian Chronic Hepatitis C Patients', Bulletin of Egyptian Society for Physiological Sciences, 28(1), pp. 141-152. doi: 10.21608/besps.2008.36844
VANCOUVER
H, Y., F, M., G, A., Ali, M., A., H. Role of Serum Interleukin–10 as a Marker of T-helper 2 Activity in Egyptian Chronic Hepatitis C Patients. Bulletin of Egyptian Society for Physiological Sciences, 2008; 28(1): 141-152. doi: 10.21608/besps.2008.36844