Document Type : Original Article
Authors
1
Biochemistry Department, Faculty of Science, King Abdulaziz University
2
Chemistry Department, Faculty of Science, Girl's Collage of Education, Jeddah, Saudi Arabia
Abstract
Frankincense, (Gum Olibanum), and Myrrh, (Commiphora merrha), are of plant
resins produce by the Burseraceae family, growing in Somali, India and Yemen. They
were known for thousands of years as one of hoarding in the east. In order to study
the therapeutic value of such resins on liver recovery after exposure to aflatoxin B1, it
was administrated intra- peritoneal to male Wister Albino rats for 10 days, after
which Frankincense and Myrrh, (each one alone), were given in the form of water
extract to rats for 20 days. At the end of the study blood from all experimental
animals was analyzed for some biochemical parameters including glucose,
triglycerides, cholesterol, urea, uric acid, creatinine, bilirubin, hemoglobin and some
key liver enzymes as asparate amino transferase (AST), alanine amino transferase
(ALT), gamma- glutamyl transferase (GGT). Liver tissue samples were analysed for
their content of total proteins, deoxyribonucleic acid (DNA), ribonucleic acid (RNA)
and in addition to histopathological examination. This study demonstrated that
Frankincense and Myrrh are of certain therapeutic recovery value in liver after
exposure to AFB1.
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