Effect of Treadmill Exercise on Nitric Oxide in Hypertensive Women

Document Type : Original Article

Authors

1 Physical Therapy Department for Cardiovascular /Respiratory Disorder and Geriatrics ,Faculty of Physical Therapy ,Cairo University

2 Internal Medicine Department, Faculty of Medicine, October 6 University.

Abstract

Back ground:Shear stress on endothelial cells is a potent stimulus for Nitric oxide
(NO) production, which is an important vasodilator. Exercise was associated with a
significant reduction in mean systolic and diastolic blood pressure. Purpose of study:
to study the effect of moderate exercises on the level of nitric oxides in hypertensive
menopause women. Method: Thirty females with post menopausal hypertension with
their ages ranged between 50-65years were divided into two equal groups: Group
(A): females receiving suitable anti-hypertensive drug & subjected to an exercise
program and then the level of nitric oxide was measured before & after the exercises
for 30min. for 3days/week for 3months. Group (B): females receiving suitable
hypertensive drug without being subjected to any exercise program & also the level of
nitric oxide was measured before & after the administration of the anti-hypertensive
drug. Results: Group (A) showed significant increase in levels of nitric oxide with
significant decrease in blood pressure & body mass index more than those of Group
(B) ( that showed significant increase in levels of nitric oxide & significant decrease
in blood pressure but of lower rates than those of Group (A)). Conclusion: the
exercises performed with moderate intensity for three months were certain beneficial
in increasing the level of nitric oxide and decreasing the level of mild hypertension in
female patients.

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